Pityriasis Rosea and Lyme
Borrelia Infection and Pityriasis Rosea Stinco G, Ruscio M, Proscia D Piccirillo F (2009) Acta Derm Venereol. ; 89(1):97-8.
Pityriasis rosea (PR) is an acute, self-limiting papulo-squamous skin disease of uncertain aetiology. Clinical and experimental findings suggest the pathogenic role of an infectious agent (1, 2). Viral and bacterial causes have been proposed, but convincing answers have not yet been
found (3). A link between Borrelia burgdorferi and PR was suggested in the 1990s and a roseolar eruption has been reported as a clinical manifestation of the second stage of Lyme disease (LD) (4, 5).
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Late Diagnosis of Early Disseminated Lyme Disease: Perplexing Symptoms in a Gardner Salzman BE, Stonehouse A and Studdiford J (2008) J Am Board Fam Med. May-Jun;21(3):234-6. PubMed: http://www.ncbi.nlm.nih.gov/pubmed/18467535
Abstract: The timely diagnosis of early disseminated Lyme disease presenting as multiple secondary erythema migrans lesions is sometimes delayed because this stage is infrequently encountered in a general practice. We report a case of a 60-year-old woman whose initial complaints of an erythematous, "burning" rash and flu-like symptoms led to several laboratory tests with no specific diagnosis. The correct diagnosis was only made after sorting through other possibilities in the differential diagnosis. By reproducing the medical images and reviewing the medical literature, we underscore the importance of including Lyme disease in the list of diagnoses pertaining to diffuse skin rashes in the febrile patient.
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